Valerenic acid is a sesquiterpenoid that acts as a positive allosteric modulator of GABAA receptors, particularly enhancing the function of receptors containing the β3 subunit. Its anxiolytic properties are primarily mediated through this modulation. Additionally, Valerenic acid serves as a partial agonist at the 5-HT5a receptor and exhibits significant antioxidant activity, making it valuable in research related to anxiety disorders and oxidative stress.
Valerenic acid is a sesquiterpenoid that acts as a positive allosteric modulator of GABAA receptors, particularly enhancing the function of receptors containing the β3 subunit. Its anxiolytic properties are primarily mediated through this modulation. Additionally, Valerenic acid serves as a partial agonist at the 5-HT5a receptor and exhibits significant antioxidant activity, making it valuable in research related to anxiety disorders and oxidative stress.
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