Valproic acid-d4-1 is a deuterated form of Valproic acid, which functions as a histone deacetylase (HDAC) inhibitor. It exhibits biological activity by inhibiting HDAC1 and promoting the proteasomal degradation of HDAC2, contributing to its role in cancer research through the activation of Notch1 signaling and inhibition of proliferation in small cell lung cancer cells. This reagent is valuable for studies in neuropharmacology and cancer biology, particularly in assessing the effects of deuterated metabolites on therapeutic outcomes and drug metabolism.
Valproic acid-d4-1 is a deuterated form of Valproic acid, which functions as a histone deacetylase (HDAC) inhibitor. It exhibits biological activity by inhibiting HDAC1 and promoting the proteasomal degradation of HDAC2, contributing to its role in cancer research through the activation of Notch1 signaling and inhibition of proliferation in small cell lung cancer cells. This reagent is valuable for studies in neuropharmacology and cancer biology, particularly in assessing the effects of deuterated metabolites on therapeutic outcomes and drug metabolism.
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