Vandetanib-13C6 is a stable carbon isotope-labeled form of Vandetanib, which serves as a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity with an IC50 of 40 nM. In addition, it effectively inhibits the tyrosine kinase activity of VEGFR3/FLT4 (IC50 of 110 nM) and EGFR/HER1 (IC50 of 500 nM). This reagent is valuable for biological research applications involving cancer signaling pathways, pharmacokinetics, and biomarker studies.
Vandetanib-13C6 is a stable carbon isotope-labeled form of Vandetanib, which serves as a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity with an IC50 of 40 nM. In addition, it effectively inhibits the tyrosine kinase activity of VEGFR3/FLT4 (IC50 of 110 nM) and EGFR/HER1 (IC50 of 500 nM). This reagent is valuable for biological research applications involving cancer signaling pathways, pharmacokinetics, and biomarker studies.
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