VD2173

Catalog No.: A77685
HGF-activating Serine Proteases Inhibitor
VD2173 is a macrocyclic peptide inhibitor specifically targeting HGF-activating serine proteases, including matriptase and hepsin. Demonstrating potent inhibition, VD2173 serves as a valuable tool for investigating the role of these proteases in various biological processes. Its use in research on lung cancer can elucidate mechanisms of tumor progression and potential therapeutic interventions.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVD2173 is a macrocyclic peptide inhibitor specifically targeting HGF-activating serine proteases, including matriptase and hepsin. Demonstrating potent inhibition, VD2173 serves as a valuable tool for investigating the role of these proteases in various biological processes. Its use in research on lung cancer can elucidate mechanisms of tumor progression and potential therapeutic interventions.
Product Information
Catalog NumA77685
FormulaC31H45N9O6S
Molecular Weight671.81
CAS Number2574389-19-6
SMILESO=C1N[C@H](C(N[C@H](C(C2=NC3=CC=CC=C3S2)=O)CCCNC(N)=N)=O)CCCCNC(C[C@H](NC(C)=O)C(N[C@H]1CC(C)C)=O)=O
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