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TLR4 Inhibitor

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Catalog No. A12548

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
VGX-1027 5mg A12548-5

Regular Price: $40.00

Special Price: $36.00

VGX-1027 10mg A12548-10

Regular Price: $60.00

Special Price: $54.00

VGX-1027 25mg A12548-25

Regular Price: $120.00

Special Price: $108.00

VGX-1027 50mg A12548-50

Regular Price: $200.00

Special Price: $180.00

VGX-1027 10mM * 1mL in DMSO A12548-10mM-D

Regular Price: $75.00

Special Price: $67.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling.


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Chemical Information

Catalog Num A12548
Actions Inhibitor
M. Wt 205.21
Formula C11H11NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 6501-72-0
Synonyms GIT 27, VGX1027, GIT27

Biological Activity

VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling.


Solubility (25°C)* In vitro DMSO 41 mg/mL (199.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 41 mg/mL (199.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.73 mL 243.65 mL 487.31mL
0.5 mM 9.75 mL 48.73 mL 97.46 mL
1 mM 4.87 mL 24.37 mL 48.73 mL
5 mM 0.97 mL 4.87 mL 9.75 mL

*The above data is based on the productmolecular weight 205.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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