VH032-PEG3-acetylene is an E3 ligase ligand-linker conjugate that integrates the VH032-based VHL ligand with a PEG3 linker, suitable for use in PROTAC technology. This compound features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-functionalized molecules. Its design facilitates the development of bifunctional molecules for targeted protein degradation studies and other applications in chemical biology research.
VH032-PEG3-acetylene is an E3 ligase ligand-linker conjugate that integrates the VH032-based VHL ligand with a PEG3 linker, suitable for use in PROTAC technology. This compound features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-functionalized molecules. Its design facilitates the development of bifunctional molecules for targeted protein degradation studies and other applications in chemical biology research.
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