Vicasinabin (RG7774) is an orally active, selective full agonist of the cannabinoid receptor type 2 (CB2R), exhibiting EC50 values of 2.81 nM for human CB2R and 2.60 nM for mouse CB2R. By selectively activating CB2R, Vicasinabin effectively inhibits inflammatory responses, reduces leukocyte adhesion, and decreases vascular permeability. This compound is valuable for research focused on conditions such as diabetic retinopathy, uveitis, and laser-induced choroidal neovascularization.
Vicasinabin (RG7774) is an orally active, selective full agonist of the cannabinoid receptor type 2 (CB2R), exhibiting EC50 values of 2.81 nM for human CB2R and 2.60 nM for mouse CB2R. By selectively activating CB2R, Vicasinabin effectively inhibits inflammatory responses, reduces leukocyte adhesion, and decreases vascular permeability. This compound is valuable for research focused on conditions such as diabetic retinopathy, uveitis, and laser-induced choroidal neovascularization.
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