VL285 Phenol is a phenol-based analog of VL285, serving as a ligand for the E3 ubiquitin ligase VHL. This compound enables the synthesis of HaloPROTAC3, facilitating the degradation of HaloTag7 fusion proteins with an IC50 of 0.34 μM. It is a valuable tool for research applications involving targeted protein degradation and the study of protein homeostasis in cellular systems.
VL285 Phenol is a phenol-based analog of VL285, serving as a ligand for the E3 ubiquitin ligase VHL. This compound enables the synthesis of HaloPROTAC3, facilitating the degradation of HaloTag7 fusion proteins with an IC50 of 0.34 μM. It is a valuable tool for research applications involving targeted protein degradation and the study of protein homeostasis in cellular systems.
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