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- Cansu Tekin, .et al. PAR1 signaling on tumor cells limits tumor growth by maintaining a mesenchymal phenotype in pancreatic cancer, Oncotarget, 2018, Aug 10; 9(62): 32010-32023 PMID: 30174793
- Claushuis TA, .et al. Thrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions, J Thromb Haemost, 2017, Apr;15(4):744-757 PMID: 28092405
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|Storage||at -20°C 3 years Powder|
|Synonyms||SCH530348, SCH-530348, MK-5348, MK5348, MK 5348|
|SMILES||CCOC(=O)N[[email protected]@H]1CC[[email protected]@H]2[[email protected]@H](C1)C[[email protected]@H]3[[email protected]]([[email protected]]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[[email protected]](OC3=O)C|
|Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||20.3 mL||101.51 mL||203.01mL|
|0.5 mM||4.06 mL||20.3 mL||40.6 mL|
|1 mM||2.03 mL||10.15 mL||20.3 mL|
|5 mM||0.41 mL||2.03 mL||4.06 mL|
*The above data is based on the productmolecular weight 492.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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