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Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.
Targets
| PAR-1 | ||||
| 8.1 nM(Ki) |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.3 mL | 101.51 mL | 203.01 mL |
| 0.5 mM | 4.06 mL | 20.3 mL | 40.6 mL |
| 1 mM | 2.03 mL | 10.15 mL | 20.3 mL |
| 5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
*The above data is based on the productmolecular weight 492.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A12832 |
|---|---|
| Actions | Antagonist |
| M. Wt | 492.58 |
| Formula | C29H33FN2O4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 618385-01-6 |
| Synonyms | SCH530348, SCH-530348, MK-5348, MK5348, MK 5348 |
| SMILES | CCOC(=O)N[[email protected]@H]1CC[[email protected]@H]2[[email protected]@H](C1)C[[email protected]@H]3[[email protected]]([[email protected]]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[[email protected]](OC3=O)C |
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