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Vorapaxar (SCH 530348)

Catalog No.: A12832
PAR-1 Antagonist
Adooq's Vorapaxar (SCH 530348) has been cited by 8 publications
Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.
Vorapaxar (SCH 530348)
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$125.00
In stock
10mg
$220.00
In stock
25mg
$405.00
In stock
50mg
$610.00
In stock
100mg
$870.00
In stock
500mg
$1,745.00
In stock
10mM * 1mL in DMSO
$155.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Vorapaxar (SCH 530348) has been cited by 8 publications
  • Arundhasa Chandrabalan, .et al. , Am J Physiol Cell Physiol, 2023, Jul 1;325(1):C272-C285 PMID: 37273236
  • Arundhasa Chandrabalan, .et al. , Sci Rep, 2023, Jan 20;13(1):1124 PMID: 36670151
  • Cansu Tekin, .et al. , Cell Oncol (Dordr), 2020, Aug 18 PMID: 32809114
  • Cansu Tekin, .et al. , Oncotarget, 2018, Aug 10; 9(62): 32010-32023 PMID: 30174793
  • Claushuis TA, .et al. , J Thromb Haemost, 2017, Apr;15(4):744-757 PMID: 28092405
  • Maaike Waasdorp, .et al. , Biochem Biophys Rep, 2017, Jul; 10: 152-156 PMID: 29114573
  • Joseph C. Mudd, .et al. , J Infect Dis, 2016, Dec 15; 214(12): 1808-1816 PMID: 27703039
  • Corey E. Tabit, .et al. , Circulation, 2016, Jul 12; 134(2): 141-152 PMID: 27354285
    • Biological Activity
    Discription Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A12832
    Formula C29H33FN2O4
    Molecular Weight 492.58
    CAS Number 618385-01-6
    SMILES CCOC(=O)N[C@@H]1CC[C@@H]2[C@@H](C1)C[C@@H]3[C@H]([C@H]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[C@H](OC3=O)C
    Synonyms SCH530348, SCH-530348, MK-5348, MK5348, MK 5348
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO 96 mg/mL (194.89 mM)
    Water Insoluble
    Ethanol 96 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.3 mL 101.51 mL 203.01 mL
    0.5 mM 4.06 mL 20.3 mL 40.6 mL
    1 mM 2.03 mL 10.15 mL 20.3 mL
    5 mM 0.41 mL 2.03 mL 4.06 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

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    • Calculator Reset
    GPCR/G Protein > Protease-Activated Receptors (PAR)
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