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Publications citing Adooq Products
Chemical Information
| Catalog Num | A14158 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 401.44 |
| Formula | C18H19N5O4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 175414-77-4 |
| Synonyms | N/A |
| SMILES code | CN[[email protected]]1CN(C[[email protected]@H]1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O |
| Chemical Name | 7-((3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl)-4-oxo-1-(thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid. |
Description |
Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication | |||||
| Solubility (25°C)* | In vitro | DMSO | 20 mg/mL heating (49.82 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.91 mL | 124.55 mL | 249.1mL |
| 0.5 mM | 4.98 mL | 24.91 mL | 49.82 mL |
| 1 mM | 2.49 mL | 12.46 mL | 24.91 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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