Voreloxin

Catalog No.: A14158

Topoisomerase II inhibitor

Voreloxin

Voreloxin Chemical Structure

CAS NO. 175414-77-4

Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication

Availability: In stock

Package Price Qty
5 mg
$180.00
10 mg
$300.00
25 mg
$600.00
10mM * 1mL in DMSO
$236.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication
In vitro DMSO 20 mg/mL heating (49.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.55 mL 249.1 mL
0.5 mM 4.98 mL 24.91 mL 49.82 mL
1 mM 2.49 mL 12.46 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14158
Actions Inhibitor
M. Wt 401.44
Formula C18H19N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 175414-77-4
Synonyms N/A
SMILES CN[[email protected]]1CN(C[[email protected]@H]1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O

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