Voreloxin

Catalog No.: A14158

Topoisomerase II inhibitor

Voreloxin

Voreloxin Chemical Structure

CAS NO. 175414-77-4

Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication

Availability: In stock

Package Price Qty
5 mg
$180.00
10 mg
$300.00
25 mg
$600.00
10mM * 1mL in DMSO
$236.00
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Biological Activity

Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.55 mL 249.1 mL
0.5 mM 4.98 mL 24.91 mL 49.82 mL
1 mM 2.49 mL 12.46 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14158
Actions Inhibitor
CAS No. 175414-77-4
Formula C18H19N5O4S
M. Wt 401.44
Purity >98%
SMILES CN[[email protected]]1CN(C[[email protected]@H]1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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