Biological Activity
Voriconazole (Vfend) is a triazole antifungal agent that is available as a lyophilized powder for solution for intravenous infusion.
Targets
P450 | ||||
In vitro (25°C) | DMSO | 65 mg/mL (186.08 mM) | |
Water | Insoluble | ||
Ethanol | 19 mg/mL (54.39 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 7 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.63 mL | 143.14 mL | 286.29 mL |
0.5 mM | 5.73 mL | 28.63 mL | 57.26 mL |
1 mM | 2.86 mL | 14.31 mL | 28.63 mL |
5 mM | 0.57 mL | 2.86 mL | 5.73 mL |
*The above data is based on the productmolecular weight 349.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10978 |
---|---|
Actions | Inhibitor |
CAS No. | 137234-62-9 |
Formula | C16H14F3N5O |
M. Wt | 349.3 |
Solubility | DMSO |
Purity | >98% |
Synonyms | Vfend,Pfizer |
SMILES | C[[email protected]@H](C1=NC=NC=C1F)[[email protected]](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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