VPC-13789

Catalog No.: A85045
Antiandrogen
VPC-13789 is a selective antiandrogen that effectively inhibits androgen receptor (AR) transcriptional activity, with an IC50 value of 0.19 μM in LNCaP cells. This compound is orally bioavailable and serves as a valuable research tool in the study of castration-resistant prostate cancer (CRPC) therapeutics. Its potency and specificity make it suitable for elucidating AR-mediated signaling pathways and developing targeted treatment strategies.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVPC-13789 is a selective antiandrogen that effectively inhibits androgen receptor (AR) transcriptional activity, with an IC50 value of 0.19 μM in LNCaP cells. This compound is orally bioavailable and serves as a valuable research tool in the study of castration-resistant prostate cancer (CRPC) therapeutics. Its potency and specificity make it suitable for elucidating AR-mediated signaling pathways and developing targeted treatment strategies.
Product Information
Catalog NumA85045
FormulaC21H16F3N3O
Molecular Weight383.37
CAS Number2761146-51-2
SMILESO=C(C1=C2C=CC(C3=CNC4=C3C=C(F)C(F)=C4F)=NC2=CC=C1)NC(C)C
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