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VTX-2337 is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activities.
Targets
| TLR8 | ||||
| 100 nM(EC50) |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.81 mL | 109.03 mL | 218.05 mL |
| 0.5 mM | 4.36 mL | 21.81 mL | 43.61 mL |
| 1 mM | 2.18 mL | 10.9 mL | 21.81 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.36 mL |
*The above data is based on the productmolecular weight 458.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12841 |
|---|---|
| Actions | Agonist |
| M. Wt | 458.6 |
| Formula | C28H34N4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 926927-61-9 |
| Synonyms | VTX2337, VTX 2337 |
| SMILES | CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCCC4)N=C(C1)N |
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