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VTX-2337 is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activities.
Targets
| TLR8 | ||||
| 100 nM(EC50) |
| In vitro | DMSO | Warmed: 48 mg/mL (104.67 mM) | |
| Water | Insoluble | ||
| Ethanol | 13 mg/mL (28.34 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.81 mL | 109.03 mL | 218.05 mL |
| 0.5 mM | 4.36 mL | 21.81 mL | 43.61 mL |
| 1 mM | 2.18 mL | 10.9 mL | 21.81 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.36 mL |
*The above data is based on the productmolecular weight 458.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12841 |
|---|---|
| Actions | Agonist |
| CAS No. | 926927-61-9 |
| Formula | C28H34N4O2 |
| M. Wt | 458.6 |
| Purity | >98% |
| Synonyms | VTX2337, VTX 2337 |
| SMILES | CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCCC4)N=C(C1)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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