VU 0361737

Catalog No.: A12467

mGlu4 receptors modulator

VU 0361737

VU 0361737 Chemical Structure

CAS NO. 1161205-04-4

VU 0361737 is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and 110 nM at human and rat receptors respectively).

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$150.00
50 mg
$240.00
10mM * 1mL in DMSO
$55.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

VU 0361737 is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and 110 nM at human and rat receptors respectively).
Targets
mGluR4 (Rat ) mGluR4 (Human)
110 nM(EC50)240 nM(EC50)
In vitro DMSO 53 mg/mL (201.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.07 mL 190.34 mL 380.68 mL
0.5 mM 7.61 mL 38.07 mL 76.14 mL
1 mM 3.81 mL 19.03 mL 38.07 mL
5 mM 0.76 mL 3.81 mL 7.61 mL

*The above data is based on the productmolecular weight 262.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12467
Actions Modulator
M. Wt 262.69
Formula C13H11ClN2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1161205-04-4
Synonyms VU-0361737, VU0361737
SMILES COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl

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