VU 0364439

Catalog No.: A12664

GluR modulator

VU 0364439

VU 0364439 Chemical Structure

CAS NO. 1246086-78-1

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).

Availability: In stock

Package Price Qty
10 mg
$60.00
25 mg
$120.00
50 mg
$200.00
100 mg
$650.00
10mM * 1mL in DMSO
$84.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
Targets
mGluR4
19.8 nM(EC50)
In vitro DMSO 85 mg/mL (201.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.68 mL 118.4 mL 236.8 mL
0.5 mM 4.74 mL 23.68 mL 47.36 mL
1 mM 2.37 mL 11.84 mL 23.68 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 422.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12664
Actions Modulator
M. Wt 422.29
Formula C18H13Cl2N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1246086-78-1
Synonyms VU0364439,VU-0364439
SMILES C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy VU 0364439 | VU 0364439 Supplier | purchase VU 0364439 | VU 0364439 cost | VU 0364439 manufacturer | order VU 0364439 | VU 0364439 distributor | buy 1246086-78-1| 1246086-78-1 Supplier | purchase 1246086-78-1 | 1246086-78-1 cost | 1246086-78-1 manufacturer | order 1246086-78-1 | 1246086-78-1 distributor
Rewards