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CFTR corrector

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Catalog No. A12519

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
VX-661 5mg A12519-5
VX-661 10mg A12519-10
VX-661 25mg A12519-25
VX-661 50mg A12519-50
VX-661 10mM * 1mL in DMSO A12519-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

VX-661 is another cystic fibrosis transmembrane conductance regulator (CFTR) corrector in development for the treatment of cystic fibrosis.


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Chemical Information

Catalog Num A12519
Actions N/A
M. Wt 520.5
Formula C26H27F3N2O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1152311-62-0
Synonyms VX661, VX 661
SMILES CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[[email protected]](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F

Biological Activity

VX-661 is another cystic fibrosis transmembrane conductance regulator (CFTR) corrector in development for the treatment of cystic fibrosis.
F508del-CFTR (Cell-free assay)


Solubility (25°C)* In vitro DMSO 100 mg/mL (192.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.21 mL 96.06 mL 192.12mL
0.5 mM 3.84 mL 19.21 mL 38.42 mL
1 mM 1.92 mL 9.61 mL 19.21 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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