VX-809 (Lumacaftor)

VX-809 is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF).
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Product Name Price Stock Qty
VX-809 5mg
Special Price $36.00 Regular Price $45.00
In stock
VX-809 10mg
Special Price $52.00 Regular Price $65.00
In stock
VX-809 50mg
Special Price $80.00 Regular Price $100.00
In stock
VX-809 10mM * 1mL in DMSO
Special Price $52.00 Regular Price $65.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VX-809 (Lumacaftor) has been cited by 5 publications
  • Daichi Hinata, .et al. , Int J Mol Sci, 2023, Jan 24;24(3):2305 PMID: 36768629
  • Kusumika Saha, .et al. , Cell Mol Life Sci, 2022, Sep 27;79(10):530 PMID: 36167862
  • Heledd H Jarosz-Griffiths, .et al. , Elife, 2020, Mar 2;9:e54556 PMID: 32118580
  • Okiyoneda T, .et al. , Dev Cell, 2018, Mar 26;44(6):694-708.e7 PMID: 29503157
  • Junko Kido, .et al. , Infect Immun, 2017, Oct; 85(10): e00311-17 PMID: 28784926
  • Biological Activity
    Discription VX-809 is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF).
    Targets
    Target Value
    Product Information
    Catalog Num A10986
    Formula C24H18F2N2O5
    Molecular Weight 452.4
    CAS Number 936727-05-8
    SMILES CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O
    Synonyms VX809
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 88 mg/mL (194.51 mM)
    Water Insoluble
    Ethanol 6 mg/mL (13.26 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.1 mL 110.52 mL 221.04 mL
    0.5 mM 4.42 mL 22.1 mL 44.21 mL
    1 mM 2.21 mL 11.05 mL 22.1 mL
    5 mM 0.44 mL 2.21 mL 4.42 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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