WAY-126299A is an orally active dual inhibitor of 5-lipoxygenase, demonstrating an IC50 of 12.2 μM, and serves as a leukotriene D4 antagonist with a pKB of 6.4. This compound effectively inhibits antigen-induced leukotriene-dependent bronchoconstriction. WAY-126299A is valuable in research related to asthma and other inflammatory conditions where leukotriene signaling plays a critical role.
WAY-126299A is an orally active dual inhibitor of 5-lipoxygenase, demonstrating an IC50 of 12.2 μM, and serves as a leukotriene D4 antagonist with a pKB of 6.4. This compound effectively inhibits antigen-induced leukotriene-dependent bronchoconstriction. WAY-126299A is valuable in research related to asthma and other inflammatory conditions where leukotriene signaling plays a critical role.
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