Wiskostatin

Catalog No.: A13903

Wiskostatin

Wiskostatin Chemical Structure

CAS NO. 253449-04-6

Wiskostatin is a cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. The compound acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Wiskostatin also binds to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$200.00
50 mg
$320.00
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Biological Activity

Wiskostatin is a cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. The compound acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Wiskostatin also binds to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.47 mL 117.33 mL 234.66 mL
0.5 mM 4.69 mL 23.47 mL 46.93 mL
1 mM 2.35 mL 11.73 mL 23.47 mL
5 mM 0.47 mL 2.35 mL 4.69 mL

*The above data is based on the productmolecular weight 426.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13903
CAS No. 253449-04-6
Formula C17H18Br2N2O
M. Wt 426.15
Purity >98%
SMILES CN(C)CC(CN1C2=C(C=C(C=C2)Br)C3=C1C=CC(=C3)Br)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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