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WY-135

Catalog No.: A20071

ALK/ ROS1 dual inhibitor

WY-135

WY-135 Chemical Structure

CAS NO. 2163060-83-9

WY-135 is an ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

WY-135 is an ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.34 mL 81.68 mL 163.36 mL
0.5 mM 3.27 mL 16.34 mL 32.67 mL
1 mM 1.63 mL 8.17 mL 16.34 mL
5 mM 0.33 mL 1.63 mL 3.27 mL

*The above data is based on the productmolecular weight 612.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20071
Actions Inhibitor
CAS No. 2163060-83-9
Formula C28H34ClN9O3S
M. Wt 612.15
Purity >98%
Synonyms WY135, WY 135
SMILES CC(C)S(C1=C(NC2=NC(NC3=C(OC)C=C(N4C=C(CN5CCN(C)CC5)N=N4)C=C3)=NC=C2Cl)C=CC=C1)(=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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