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Biological Activity
WY-135 is an ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.34 mL | 81.68 mL | 163.36 mL |
| 0.5 mM | 3.27 mL | 16.34 mL | 32.67 mL |
| 1 mM | 1.63 mL | 8.17 mL | 16.34 mL |
| 5 mM | 0.33 mL | 1.63 mL | 3.27 mL |
*The above data is based on the productmolecular weight 612.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20071 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2163060-83-9 |
| Formula | C28H34ClN9O3S |
| M. Wt | 612.15 |
| Purity | >98% |
| Synonyms | WY135, WY 135 |
| SMILES | CC(C)S(C1=C(NC2=NC(NC3=C(OC)C=C(N4C=C(CN5CCN(C)CC5)N=N4)C=C3)=NC=C2Cl)C=CC=C1)(=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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