WZ3146

Catalog No.: A10990
EGFR Inhibitor
WZ3146 is an inhibitor of EGFR receptor kinase mutants carrying a mutation in an active site gatekeeper residue (T790M) and is much less potent against wild-type EGFR kinase.
Grouped product items
Product Name Price Stock Qty
WZ3146 5mg
$70.00
In stock
WZ3146 10mg
$120.00
In stock
WZ3146 50mg
$350.00
In stock
WZ3146 100mg
$600.00
In stock
WZ3146 10mM * 1mL in DMSO
$124.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription WZ3146 is an inhibitor of EGFR receptor kinase mutants carrying a mutation in an active site gatekeeper residue (T790M) and is much less potent against wild-type EGFR kinase.
Targets
Target Value
Product Information
Catalog Num A10990
Formula C24H25ClN6O2
Molecular Weight 465
CAS Number 1214265-56-1
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl
Synonyms WZ-3146
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 83 mg/mL (178.51 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.51 mL 107.53 mL 215.05 mL
0.5 mM 4.3 mL 21.51 mL 43.01 mL
1 mM 2.15 mL 10.75 mL 21.51 mL
5 mM 0.43 mL 2.15 mL 4.3 mL
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