Xaliproden hydrochloride is a potent, selective agonist of the 5-HT1A receptor, demonstrating high affinity for specific binding sites in the rat hippocampus (IC50 = 3 nM). Additionally, it acts as a selective antagonist of the dopamine D2 receptor with moderate affinity (IC50 = 0.1-1 μM). Xaliproden hydrochloride exhibits significant anti-depressant and anti-anxiety effects, making it a valuable compound for investigating therapeutic approaches in neurodegenerative disease research.
Xaliproden hydrochloride is a potent, selective agonist of the 5-HT1A receptor, demonstrating high affinity for specific binding sites in the rat hippocampus (IC50 = 3 nM). Additionally, it acts as a selective antagonist of the dopamine D2 receptor with moderate affinity (IC50 = 0.1-1 μM). Xaliproden hydrochloride exhibits significant anti-depressant and anti-anxiety effects, making it a valuable compound for investigating therapeutic approaches in neurodegenerative disease research.
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