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Xanthine oxidase-IN-8

Catalog No.: A78161
XOD Inhibitor
Xanthine oxidase-IN-8 (Icarisids J) is a selective inhibitor of xanthine oxidase (XOD) with an IC50 value of 29.71 μM. This compound demonstrates significant activity in reducing uric acid production, making it useful for studying conditions associated with hyperuricemia, such as gout. Its inhibitory effects on XOD can assist in elucidating the enzyme's role in various metabolic pathways and potential therapeutic interventions.
Xanthine oxidase-IN-8 2571069-66-2 XOD Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXanthine oxidase-IN-8 (Icarisids J) is a selective inhibitor of xanthine oxidase (XOD) with an IC50 value of 29.71 μM. This compound demonstrates significant activity in reducing uric acid production, making it useful for studying conditions associated with hyperuricemia, such as gout. Its inhibitory effects on XOD can assist in elucidating the enzyme's role in various metabolic pathways and potential therapeutic interventions.
Product Information
Catalog NumA78161
FormulaC44H58O23
Molecular Weight954.92
CAS Number2571069-66-2
SMILESC/C(C)=C\CC1=C2C(C(C(O[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O[C@@]4([H])[C@@H]([C@H]([C@@H](CO4)O)O)O)=C(C5=CC=C(C=C5)OC)O2)=O)=C(C=C1O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O[C@@]7([H])[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)O)O)O
SynonymsIcarisids J
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Metabolism > Xanthine Oxidase