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Xilmenolone

Catalog No.: A66821
GABAA Receptor PAM
Xilmenolone is a positive allosteric modulator of the GABAA receptor, enhancing its activity and facilitating neurotransmission. This compound exhibits notable anxiolytic and sedative properties, making it a valuable tool in neuropharmacological research. Xilmenolone can be utilized to study the modulation of GABAergic signaling and its implications in various neurological disorders.
Xilmenolone 2368807-26-3 GABAA Receptor PAM
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXilmenolone is a positive allosteric modulator of the GABAA receptor, enhancing its activity and facilitating neurotransmission. This compound exhibits notable anxiolytic and sedative properties, making it a valuable tool in neuropharmacological research. Xilmenolone can be utilized to study the modulation of GABAergic signaling and its implications in various neurological disorders.
Product Information
Catalog NumA66821
FormulaC26H37N3O2
Molecular Weight423.59
CAS Number2368807-26-3
SMILESC[C@@]12[C@]([C@@H](C[C@@H]2C(CN3N=C(C=C3)C#N)=O)C)([H])[C@@]4([H])[C@]([C@]5([H])[C@](C[C@](O)(CC5)C)([H])CC4)([H])CC1
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Neuronal Signaling > GABA Receptors