XL-888

Catalog No.: A11251

HSP90 Inhibitor

XL-888

XL-888 Chemical Structure

CAS NO. 1149705-71-4

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $110.00

Special Price $99.00

10 mg

Regular Price: $200.00

Special Price $180.00

25 mg

Regular Price: $400.00

Special Price $360.00

50 mg

Regular Price: $700.00

Special Price $630.00

10mM * 1mL in DMSO

Regular Price: $170.00

Special Price $153.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
Targets
HSP90
24 nM
In vitro (25°C) DMSO 100 mg/mL (198.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.28 mL 198.56 mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11251
Actions Inhibitor
M. Wt 503.63
Formula C29H37N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1149705-71-4
Synonyms XL888; XL-888; XL 888
SMILES CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[[email protected]]3CC[[email protected]@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5

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