XL-888

Catalog No.: A11251

HSP90 Inhibitor

XL-888

XL-888 Chemical Structure

CAS NO. 1149705-71-4

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$200.00
25 mg
$400.00
50 mg
$700.00
10mM * 1mL in DMSO
$170.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
Targets
HSP90
24 nM
In vitro (25°C) DMSO 99 mg/mL (196.56 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.28 mL 198.56 mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11251
Actions Inhibitor
CAS No. 1149705-71-4
Formula C29H37N5O3
M. Wt 503.63
Purity >98%
Synonyms XL888; XL-888; XL 888
SMILES CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[[email protected]]3CC[[email protected]@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy XL-888 | XL-888 Supplier | purchase | cost | manufacturer | order | distributor | buy 1149705-71-4| 1149705-71-4 Supplier | purchase 1149705-71-4 | 1149705-71-4 cost | 1149705-71-4 manufacturer | order 1149705-71-4 | 1149705-71-4 distributor
Rewards