XL-888

Catalog No.: A11251
HSP90 Inhibitor
XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
5mg
$105.00
In stock
10mg
$195.00
In stock
25mg
$390.00
In stock
50mg
$590.00
In stock
100mg
$860.00
In stock
10mM * 1mL in DMSO
$140.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's XL-888 has been cited by 2 publications
  • ?zlem Kaplan, .et al. , Med Oncol, 2024, Jul 3;41(8):194 PMID: 38958814
  • Ozlem Kaplan, .et al. , Med Oncol, 2023, Oct 4;40(11):318 PMID: 37794195
  • Biological Activity
    Discription XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11251
    Formula C29H37N5O3
    Molecular Weight 503.63
    CAS Number 1149705-71-4
    SMILES CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[C@H]3CC[C@@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5
    Synonyms XL888; XL-888; XL 888
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 99 mg/mL (196.56 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.86 mL 99.28 mL 198.56 mL
    0.5 mM 3.97 mL 19.86 mL 39.71 mL
    1 mM 1.99 mL 9.93 mL 19.86 mL
    5 mM 0.4 mL 1.99 mL 3.97 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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