Xylocydine is a potent inhibitor of cyclin-dependent kinases CDK1 and CDK2, demonstrating IC50 values of 1.4 nM and 61 nM, respectively. This compound effectively disrupts CDK activity, contributing to the regulation of apoptotic processes. Additionally, Xylocydine downregulates the levels of phosphorylated nucleolin and retinoblastoma protein, making it a valuable tool for investigations into cell cycle regulation and cancer research.
Xylocydine is a potent inhibitor of cyclin-dependent kinases CDK1 and CDK2, demonstrating IC50 values of 1.4 nM and 61 nM, respectively. This compound effectively disrupts CDK activity, contributing to the regulation of apoptotic processes. Additionally, Xylocydine downregulates the levels of phosphorylated nucleolin and retinoblastoma protein, making it a valuable tool for investigations into cell cycle regulation and cancer research.
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