YL-0919

Catalog No.: A16337

5-HT1A receptor agonist/serotonin reuptake inhibitor

YL-0919

YL-0919 Chemical Structure

CAS NO. 1339058-04-6

YL0919, a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor,the IC50 values of YL-0919 inhibiting the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells were 1.78±0.34 nM and 1.93±0.18 nM respectively.

Availability: In stock

Package Price Qty
2 mg
$80.00
5 mg
$160.00
10 mg
$280.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

YL0919, a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor,the IC50 values of YL-0919 inhibiting the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells were 1.78±0.34 nM and 1.93±0.18 nM respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.87 mL 149.33 mL 298.65 mL
0.5 mM 5.97 mL 29.87 mL 59.73 mL
1 mM 2.99 mL 14.93 mL 29.87 mL
5 mM 0.6 mL 2.99 mL 5.97 mL

*The above data is based on the productmolecular weight 334.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16337
Actions Agonist, Inhibitor
M. Wt 334.84
Formula C18H23N2O2Cl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1339058-04-6
Synonyms YL-0919, YL 0919
SMILES O=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl

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