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YL-0919

5-HT1A receptor agonist/serotonin reuptake inhibitor

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Catalog No. A16337

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
YL-0919 2mg A16337-2
$80.00
YL-0919 5mg A16337-5
$160.00
YL-0919 10mg A16337-10
$280.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

YL0919, a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor,the IC50 values of YL-0919 inhibiting the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells were 1.78??0.34 nM and 1.93??0.18 nM respectively.

YL-0919

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Chemical Information

Catalog Num A16337
Actions Agonist, Inhibitor
M. Wt 334.84
Formula C18H23N2O2Cl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1339058-04-6
Synonyms YL-0919, YL 0919
SMILES O=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl

Biological Activity

Description
YL0919, a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor,the IC50 values of YL-0919 inhibiting the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells were 1.78??0.34 nM and 1.93??0.18 nM respectively.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.87 mL 149.33 mL 298.65mL
0.5 mM 5.97 mL 29.87 mL 59.73 mL
1 mM 2.99 mL 14.93 mL 29.87 mL
5 mM 0.6 mL 2.99 mL 5.97 mL

*The above data is based on the productmolecular weight 334.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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