YM-17690

Catalog No.: A61077
LTD4 Agonist
YM-17690 is a potent agonist of leukotriene D4 (LTD4) and leukotriene E4 (LTE4), exhibiting a pKi value of 9.28 for [3H]LTD4 binding. It induces dose-dependent contractions in guinea pig ileum, lung parenchyma, and trachea, with EC50 values of 16 nM, 3.9 nM, and 22 nM, respectively. This compound is valuable for research focused on asthma, inflammation, and related respiratory conditions.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionYM-17690 is a potent agonist of leukotriene D4 (LTD4) and leukotriene E4 (LTE4), exhibiting a pKi value of 9.28 for [3H]LTD4 binding. It induces dose-dependent contractions in guinea pig ileum, lung parenchyma, and trachea, with EC50 values of 16 nM, 3.9 nM, and 22 nM, respectively. This compound is valuable for research focused on asthma, inflammation, and related respiratory conditions.
Product Information
Catalog NumA61077
FormulaC28H29NO7
Molecular Weight491.53
CAS Number108806-41-3
SMILESO=C(O)CCC1=CC=C(OCC(O)=O)C(NC(C2=CC=C(OCCCCC3=CC=CC=C3)C=C2)=O)=C1
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