Z19153 is a selective phosphodiesterase 4 (PDE4) inhibitor with IC50 values of 110 nM for PDE4B1 and 1160 nM for PDE4D7. This compound demonstrates significant hepatoprotective effects in the context of hepatic sepsis, making it a valuable tool for studying inflammatory responses in liver disease. Z19153 is suitable for research applications focused on PDE4-related signaling pathways and their implications in various physiological and pathological conditions.
Z19153 is a selective phosphodiesterase 4 (PDE4) inhibitor with IC50 values of 110 nM for PDE4B1 and 1160 nM for PDE4D7. This compound demonstrates significant hepatoprotective effects in the context of hepatic sepsis, making it a valuable tool for studying inflammatory responses in liver disease. Z19153 is suitable for research applications focused on PDE4-related signaling pathways and their implications in various physiological and pathological conditions.
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