Z21090

Catalog No.: A41985
PDE4 Inhibitor
Z21090 is a selective inhibitor of phosphodiesterase-4 (PDE4), exhibiting an IC50 value of 37.4 nM and demonstrating oral bioavailability. This compound is significant for studies related to alcohol-related diseases and offers potential therapeutic insights into inflammatory processes and neurodegenerative conditions associated with PDE4 activity. Researchers may utilize Z21090 to explore its effects on cyclic AMP signaling pathways and related biological mechanisms.
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5mg
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50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionZ21090 is a selective inhibitor of phosphodiesterase-4 (PDE4), exhibiting an IC50 value of 37.4 nM and demonstrating oral bioavailability. This compound is significant for studies related to alcohol-related diseases and offers potential therapeutic insights into inflammatory processes and neurodegenerative conditions associated with PDE4 activity. Researchers may utilize Z21090 to explore its effects on cyclic AMP signaling pathways and related biological mechanisms.
Product Information
Catalog NumA41985
FormulaC12H14ClN3O3
Molecular Weight283.71
CAS Number2992690-71-6
SMILESCCOC1=NC(Cl)=CC2=C1C=NN2CCCC(O)=O
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