Zearalenone

Catalog No.: A13740

Zearalenone

Zearalenone Chemical Structure

CAS NO. 17924-92-4

Zearalenone is a phytoestrogenic mycotoxin usually produced by Fusarium species, is shown to be a cytotoxic compound, but alos binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and was found to stimulate the transcriptional activity of both subtypes at concentrations between 1 - 10 nM.

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10 mg

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25 mg

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50 mg

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100 mg

Regular Price: $280.00

Special Price $224.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Muthulakshmi S, .et al. Mycotoxin zearalenone induced gonadal impairment and altered gene expression in the hypothalamic-pituitary-gonadal axis of adult female zebrafish (Danio rerio), J Appl Toxicol, 2018, Nov;38(11):1388-1397 PMID: 29923290

Biological Activity

Zearalenone is a phytoestrogenic mycotoxin usually produced by Fusarium species, is shown to be a cytotoxic compound, but alos binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and was found to stimulate the transcriptional activity of both subtypes at concentrations between 1 - 10 nM.
In vitro DMSO 56 mg/mL (175.9 mM)
Water Insoluble
Ethanol 56 mg/mL (175.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.41 mL 157.05 mL 314.11 mL
0.5 mM 6.28 mL 31.41 mL 62.82 mL
1 mM 3.14 mL 15.71 mL 31.41 mL
5 mM 0.63 mL 3.14 mL 6.28 mL

*The above data is based on the productmolecular weight 318.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13740
CAS No. 17924-92-4
Formula C18H22O5
M. Wt 318.36
Purity >98%
SMILES C[[email protected]]1CCCC(=O)CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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