Ziritaxestat

Catalog No.: A19312
ATX inhibitor
Ziritaxestat (GLPG1690) is a first-in-class autotaxin (ATX) inhibitor, with an IC50 of 131 nM and Ki of 15 nM.
Grouped product items
Product Name Price Stock Qty
Ziritaxestat 5mg
$76.00
In stock
Ziritaxestat 10mg
$130.00
In stock
Ziritaxestat 50mg
$386.00
In stock
Ziritaxestat 100mg
$773.00
In stock
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Biological Activity
Discription Ziritaxestat (GLPG1690) is a first-in-class autotaxin (ATX) inhibitor, with an IC50 of 131 nM and Ki of 15 nM.
Targets
Target Value
Product Information
Catalog Num A19312
Formula C30H33FN8O2S
Molecular Weight 588.7
CAS Number 1628260-79-6
SMILES N#CC1=C(C2=CC=C(F)C=C2)N=C(N(C3=C(CC)N=C4C(C)=CC(N5CCN(CC(N6CC(O)C6)=O)CC5)=CN43)C)S1
Synonyms GLPG1690, GLPG-1690, GLPG 1690
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 87 mg/mL (147.78 mM)
Water Insoluble
Ethanol 3 mg/mL (5.09 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.99 mL 84.93 mL 169.87 mL
0.5 mM 3.4 mL 16.99 mL 33.97 mL
1 mM 1.7 mL 8.49 mL 16.99 mL
5 mM 0.34 mL 1.7 mL 3.4 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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