ZJY-54 is a potent dual-target inhibitor of EGFR and LSD1, exhibiting IC50 values of 3.8 nM and 0.6 μM, respectively. This compound effectively inhibits the proliferation of non-small cell lung cancer cells and promotes the accumulation of H3K4me2 and H3K9me2 modifications. Additionally, ZJY-54 disrupts the phosphorylation of the EGFR signaling pathway, demonstrating significant anti-tumor activity suitable for cancer research applications.
ZJY-54 is a potent dual-target inhibitor of EGFR and LSD1, exhibiting IC50 values of 3.8 nM and 0.6 μM, respectively. This compound effectively inhibits the proliferation of non-small cell lung cancer cells and promotes the accumulation of H3K4me2 and H3K9me2 modifications. Additionally, ZJY-54 disrupts the phosphorylation of the EGFR signaling pathway, demonstrating significant anti-tumor activity suitable for cancer research applications.
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