ZL0454

Catalog No.: A20123

BRD4 inhibitor

ZL0454

ZL0454 Chemical Structure

CAS NO. 2229042-77-5

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.71 mL 133.53 mL 267.05 mL
0.5 mM 5.34 mL 26.71 mL 53.41 mL
1 mM 2.67 mL 13.35 mL 26.71 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20123
Actions Inhibitor
CAS No. 2229042-77-5
Formula C18H22N4O3S
M. Wt 374.46
Purity >98%
Synonyms ZL 0454, ZL-0454
SMILES OC1=C(C)C=C(/N=N/C2=CC=C(S(NC3CCCC3)(=O)=O)C=C2)C(N)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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