Biological Activity
ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.71 mL | 133.53 mL | 267.05 mL |
0.5 mM | 5.34 mL | 26.71 mL | 53.41 mL |
1 mM | 2.67 mL | 13.35 mL | 26.71 mL |
5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
*The above data is based on the productmolecular weight 374.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A20123 |
---|---|
Actions | Inhibitor |
M. Wt | 374.46 |
Formula | C18H22N4O3S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2229042-77-5 |
Synonyms | ZL 0454, ZL-0454 |
SMILES | OC1=C(C)C=C(/N=N/C2=CC=C(S(NC3CCCC3)(=O)=O)C=C2)C(N)=C1 |
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