ZM 306416 hydrochloride

Catalog No.: A11955

VEGFR Inhibitor

ZM 306416 hydrochloride

ZM 306416 hydrochloride Chemical Structure

CAS NO. 690206-97-4

ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.

Availability: In stock

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10 mg
25 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.
VEGFR1 Src Abl
0.33 μM0.33 μM1.3 μM
In vitro DMSO 59 mg/mL (176.78 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.01 mL 135.06 mL 270.12 mL
0.5 mM 5.4 mL 27.01 mL 54.02 mL
1 mM 2.7 mL 13.51 mL 27.01 mL
5 mM 0.54 mL 2.7 mL 5.4 mL

*The above data is based on the productmolecular weight 370.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11955
Actions Inhibitor
CAS No. 690206-97-4
Formula C16H13N3O2FCl.HCl
M. Wt 370.21
Solubility DMSO
Purity >98%
Synonyms ZM-306416

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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