ZM 336372

Catalog No.: A11077

C-Raf inhibitor

ZM 336372

ZM 336372 Chemical Structure

CAS NO. 208260-29-1

ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $36.00

10 mg

Regular Price: $70.00

Special Price $63.00

50 mg

Regular Price: $200.00

Special Price $180.00

100 mg

Regular Price: $350.00

Special Price $315.00

10mM * 1mL in DMSO

Regular Price: $60.00

Special Price $54.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.
Targets
C-Raf
70 nM
In vitro DMSO 78 mg/mL (200.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (5.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.67 mL 128.37 mL 256.74 mL
0.5 mM 5.13 mL 25.67 mL 51.35 mL
1 mM 2.57 mL 12.84 mL 25.67 mL
5 mM 0.51 mL 2.57 mL 5.13 mL

*The above data is based on the productmolecular weight 389.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11077
Actions Inhibitor
M. Wt 389.5
Formula C23H23N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 208260-29-1
Synonyms ZM-336372, ZM336372
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O

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