Cercosporamide

Mnk2/JAK3 inhibitor

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Catalog No. A15362

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Cercosporamide 0.5mg A15362-0.5
$160.00
Cercosporamide 1mg A15362-1
$300.00
Cercosporamide 2.5mg A15362-2.5
$600.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Cercosporamide, an usnic amide, was originally identified in Cercosporidium henningsii as a host-selective phytotoxin and broad-spectrum antifungal agent and is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2; IC50 = 11 nM), JAK3 (IC50 = 31), and Mnk1 (IC50 = 116 nM).

Cercosporamide

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Chemical Information

Catalog Num A15362
Actions Inhibitor
M. Wt 331.28
Formula C16H13NO7
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 131436-22-1
Synonyms N/A
SMILES code CC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O
Chemical Name (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide

Biological Activity

Description
Cercosporamide, an usnic amide, was originally identified in Cercosporidium henningsii as a host-selective phytotoxin and broad-spectrum antifungal agent and is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2; IC50 = 11 nM), JAK3 (IC50 = 31), and Mnk1 (IC50 = 116 nM).

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