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CYT387 sulfate salt

JAK inhibitor

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Catalog No. A15056

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CYT387 sulfate salt 10mg A15056-10
CYT387 sulfate salt 50mg A15056-50
CYT387 sulfate salt 100mg A15056-100

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Quick Overview

CYT387 sulfate salt is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.

CYT387 sulfate salt

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Chemical Information

Catalog Num A15056
Actions Inhibitor
M. Wt 610.62
Formula C23H26N6O10S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1056636-06-6
Synonyms CYT-387 sulfate, CYT 387 sulfate, momelotinib sulfate
SMILES code C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)O
Chemical Name N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide; sulfuric acid

Biological Activity

CYT387 sulfate salt is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.

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