Cyt387 (Momelotinib)

Catalog No.: A10263

JAK inhibitor

Cyt387 (Momelotinib) Chemical Structure

CAS NO. 1056634-68-4

CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $280.00

Special Price $224.00

200 mg

Regular Price: $650.00

Special Price $520.00

10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.
Targets
JAK1 JAK2 JAK3
11 nM18 nM155 nM
In vitro (25°C) DMSO 83 mg/mL (200.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.13 mL 120.63 mL 241.25 mL
0.5 mM 4.83 mL 24.13 mL 48.25 mL
1 mM 2.41 mL 12.06 mL 24.13 mL
5 mM 0.48 mL 2.41 mL 4.83 mL

*The above data is based on the productmolecular weight 414.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10263
Actions Inhibitor
M. Wt 414.5
Formula C23H22N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1056634-68-4
Synonyms CYT 11387, Cyt-387
SMILES C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy Cyt387 (Momelotinib) | Cyt387 (Momelotinib) Supplier | purchase Cyt387 (Momelotinib) | Cyt387 (Momelotinib) cost | Cyt387 (Momelotinib) manufacturer | order Cyt387 (Momelotinib) | Cyt387 (Momelotinib) distributor | buy 1056634-68-4| 1056634-68-4 Supplier | purchase 1056634-68-4 | 1056634-68-4 cost | 1056634-68-4 manufacturer | order 1056634-68-4 | 1056634-68-4 distributor
Rewards