Cyt387 (Momelotinib)
Important Notice: For research use only. We do not sell to patients.
Other Forms of Cyt387 (Momelotinib)
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Important Notice: For research use only. We do not sell to patients.
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Discription | CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively. | ||
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Targets |
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Catalog Num | A10263 |
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Formula | C23H22N6O2 |
Molecular Weight | 414.5 |
CAS Number | 1056634-68-4 |
SMILES | C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 67 mg/mL (161.65 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+40%PEG 300+ 3% Tween80 + ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.13 mL | 120.63 mL | 241.25 mL |
0.5 mM | 4.83 mL | 24.13 mL | 48.25 mL |
1 mM | 2.41 mL | 12.06 mL | 24.13 mL |
5 mM | 0.48 mL | 2.41 mL | 4.83 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2