DMH-1

Catalog No.: A12820
ALK2 inhibitor
DMH-1 is a selective inhibitor of the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM).
Grouped product items
Product Name Price Stock Qty
DMH-1 10mg
$80.00
In stock
DMH-1 25mg
$150.00
In stock
DMH-1 50mg
$230.00
In stock
DMH-1 100mg
$500.00
In stock
DMH-1 10mM * 1mL in DMSO
$89.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's DMH-1 has been cited by 1 publications
  • Teresa Rayon, .et al. , Science, 2020, Sep 18;369(6510):eaba7667 PMID: 32943498
  • Biological Activity
    Discription DMH-1 is a selective inhibitor of the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A12820
    Formula C24H20N4O
    Molecular Weight 380.44
    CAS Number 1206711-16-1
    SMILES CC(C)OC1=CC=C(C=C1)C2=CN3C(=C(C=N3)C4=CC=NC5=CC=CC=C45)N=C2
    Synonyms DMH1
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 21 mg/mL (55.19 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+35% PEG 300+2% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.29 mL 131.43 mL 262.85 mL
    0.5 mM 5.26 mL 26.29 mL 52.57 mL
    1 mM 2.63 mL 13.14 mL 26.29 mL
    5 mM 0.53 mL 2.63 mL 5.26 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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