Geldanamycin

Catalog No.: A11025
Hsp90 inhibitor
Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.
Grouped product items
Product Name Price Stock Qty
Geldanamycin 5mg
$60.00
In stock
Geldanamycin 10mg
$100.00
In stock
Geldanamycin 50mg
$400.00
In stock
Geldanamycin 100mg
$600.00
In stock
Geldanamycin 10mM * 1mL in DMSO
$126.00
In stock
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Adooq Products cited in reputable paper
Adooq's Geldanamycin has been cited by 1 publications
  • Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422
  • Biological Activity
    Discription Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.
    Targets
    Target Value
    Product Information
    Catalog Num A11025
    Formula C29H40N2O9
    Molecular Weight 560.6
    CAS Number 30562-34-6
    SMILES C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C/C=C(/C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)\C)OC)OC(=O)N)\C)C)O)OC
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Warmed: 32 mg/mL (57.08 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.84 mL 89.19 mL 178.38 mL
    0.5 mM 3.57 mL 17.84 mL 35.68 mL
    1 mM 1.78 mL 8.92 mL 17.84 mL
    5 mM 0.36 mL 1.78 mL 3.57 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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