GSK2141795 (Uprosertib, GSK795)

Akt inhibitor

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Catalog No. A15809

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK2141795 5mg A15809-5
$100.00
GSK2141795 10mg A15809-10
$150.00
GSK2141795 25mg A15809-25
$370.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

GSK2141795 (Uprosertib, GSK795)

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Chemical Information

Catalog Num A15809
Actions Inhibitor
M. Wt 429.25
Formula C18H16Cl2F2N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1047634-65-0
Synonyms GSK2141795, GSK2141795, Uprosertib, GSK 795
SMILES code CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl
Chemical Name N-((S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-2-carboxamide

Biological Activity

Description
Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.
Targets
Akt3 Akt1 Akt2
38 nM180 nM328 nM

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