KN-93 Phosphate

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CaMKII inhibitor

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Catalog No. A14288

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KN-93 Phosphate 10mg A14288-10

Regular Price: $110.00

Special Price: $93.50

KN-93 Phosphate 25mg A14288-25

Regular Price: $220.00

Special Price: $187.00

KN-93 Phosphate 50mg A14288-50

Regular Price: $400.00

Special Price: $340.00

KN-93 Phosphate 10mM * 1mL in DMSO A14288-10mM-D

Regular Price: $125.00

Special Price: $106.25

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 ??M, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.

KN-93 Phosphate

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Chemical Information

Catalog Num A14288
Actions Inhibitor
M. Wt 599.03
Formula C26H29ClN2O4S. H3O4P
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1188890-41-6
Synonyms KN93, KN 93
SMILES code [HH].CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OOP(=O)=O
Chemical Name Benzenesulfonamide, N-?[2-?[[[(2E)?-?3-?(4-?chlorophenyl)?-?2-?propen-?1-?yl]?methylamino]?methyl]?phenyl]?-?N-?(2-?hydroxyethyl)?-?4-?methoxy-?, phosphate (1:1)

Biological Activity

Description
KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 ??M, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.
Targets
CaMKII
0.37 μM(Ki)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (166.93 mM)
Water 92 mg/mL (153.58 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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