NU-7441 (KU-57788) ON SALE DNA-PK inhibitor

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Catalog No. A11098

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NU-7441 (KU-57788) 5mg A11098-5

Regular Price: $50.00

Special Price: $42.50

NU-7441 (KU-57788) 10mg A11098-10

Regular Price: $90.00

Special Price: $76.50

NU-7441 (KU-57788) 50mg A11098-50

Regular Price: $180.00

Special Price: $153.00

NU-7441 (KU-57788) 100mg A11098-100

Regular Price: $300.00

Special Price: $255.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively.

NU-7441 (KU-57788)

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Chemical Information

Catalog Num A11098
Actions Inhibitor
M. Wt 413.5
Formula C25H19NO3S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 503468-95-9
Synonyms NU7441, KU57788
SMILES code C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56
Chemical Name 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one

Biological Activity

Description
NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively.

Solubility

Solubility (25°C)* In vitro DMSO 3 mg/mL (7.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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