PI-103 Hydrochloride

Catalog No.: A15212
PI3K Inhibitor
PI103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.
Grouped product items
Product Name Price Stock Qty
PI-103 Hydrochloride 10mg
$65.00
In stock
PI-103 Hydrochloride 50mg
$200.00
In stock
PI-103 Hydrochloride 100mg
$360.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription PI103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.
Targets
Target Value
Product Information
Catalog Num A15212
Formula C19H17ClN4O3
Molecular Weight 384.82
CAS Number 371935-79-4
SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl
Synonyms PI 103 hydrochloride, PI103 hydrochloride
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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