PI-103 Hydrochloride

PI3K Inhibitor

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Catalog No. A15212

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PI-103 Hydrochloride 10mg A15212-10
$65.00
PI-103 Hydrochloride 50mg A15212-50
$200.00
PI-103 Hydrochloride 100mg A15212-100
$360.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PI103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.

PI-103 Hydrochloride

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Chemical Information

Catalog Num A15212
Actions Inhibitor
M. Wt 384.82
Formula C19H17ClN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 371935-79-4
Synonyms PI 103 hydrochloride, PI103 hydrochloride
SMILES code C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl
Chemical Name 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride

Biological Activity

Description
PI103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM.

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