PI-103

Catalog No.: A10726
PI3K Inhibitor
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.
Grouped product items
Product Name Price Stock Qty
PI-103 5mg
Special Price $40.00 Regular Price $50.00
In stock
PI-103 10mg
Special Price $56.00 Regular Price $70.00
In stock
PI-103 25mg
Special Price $112.00 Regular Price $140.00
In stock
PI-103 50mg
Special Price $176.00 Regular Price $220.00
In stock
PI-103 10mM * 1mL in DMSO
Special Price $75.20 Regular Price $94.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PI-103 has been cited by 2 publications
  • Diane Yang, .et al. , Diabetes, 2021, Oct;70(10):2419-2429 PMID: 34344789
  • Byungki Jang, .et al. , Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055
  • Biological Activity
    Discription PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.
    Targets
    Target Value
    Product Information
    Catalog Num A10726
    Formula C19H16N4O3
    Molecular Weight 348.4
    CAS Number 371935-74-9
    SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 22 mg/mL (63.15 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.7 mL 143.51 mL 287.03 mL
    0.5 mM 5.74 mL 28.7 mL 57.41 mL
    1 mM 2.87 mL 14.35 mL 28.7 mL
    5 mM 0.57 mL 2.87 mL 5.74 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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