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PI3K Inhibitor

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Catalog No. A10726

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PI-103 5mg A10726-5

Regular Price: €47.50

Special Price: €42.75

PI-103 10mg A10726-10

Regular Price: €66.50

Special Price: €59.85

PI-103 25mg A10726-25

Regular Price: €133.00

Special Price: €119.70

PI-103 50mg A10726-50

Regular Price: €209.00

Special Price: €188.10

PI-103 10mM * 1mL in DMSO A10726-10mM-D

Regular Price: €89.30

Special Price: €80.37

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.


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Publications citing Adooq Products
PI-103 Citations (1)
  • Byungki Jang, .et al. The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells, Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Chemical Information

Catalog Num A10726
Actions Inhibitor
M. Wt 348.4
Formula C19H16N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 371935-74-9
Synonyms PI103

Biological Activity

PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.
Target Value
p110αIC50: 2nM
p110βIC50: 3nM
p110δIC50: 3nM
p110γIC50: 15nM
DNA-PKIC50: 23nM
mTORIC50: 30nM


Solubility (25°C) * In vitro DMSO 24 mg/mL (68.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.7 mL 143.51 mL 287.03mL
0.5 mM 5.74 mL 28.7 mL 57.41 mL
1 mM 2.87 mL 14.35 mL 28.7 mL
5 mM 0.57 mL 2.87 mL 5.74 mL

*The above data is based on the productmolecular weight 348.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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