Plerixafor 8HCl (DB06809)

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CXCR antagonist

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Catalog No. A10913

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Plerixafor 8HCl 10mg A10913-10

Regular Price: $60.00

Special Price: $51.00

Plerixafor 8HCl 25mg A10913-25

Regular Price: $100.00

Special Price: $85.00

Plerixafor 8HCl 50mg A10913-50

Regular Price: $160.00

Special Price: $136.00

Plerixafor 8HCl 100mg A10913-100

Regular Price: $310.00

Special Price: $263.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.

Plerixafor 8HCl (DB06809)

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Chemical Information

Catalog Num A10913
Actions Antagonist
M. Wt 794.5
Formula C28H54N8.8HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 155148-31-5
Synonyms DB06809, AMD3100, Mozobil
SMILES code C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl
Chemical Name 1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)

Biological Activity

Description
Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.
Targets
CXCL12-mediated chemotaxis (Cell-free assay) CXCR4 (Cell-free assay)
5.7 nM44 nM

Solubility

Solubility (25°C) * In vitro DMSO <1 mg/mL (<1 mM)
Water 100 mg/mL (125.87 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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