Reversine

Catalog No.: A13250
human A3 adenosine receptor antagonist /Aurora inhibitor
Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.
Grouped product items
Product Name Price Stock Qty
Reversine 5mg
$60.00
In stock
Reversine 10mg
$90.00
In stock
Reversine 25mg
$180.00
In stock
Reversine 50mg
$250.00
In stock
Reversine 10mM * 1mL in DMSO
$75.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Reversine has been cited by 2 publications
  • Amy H. Ide, .et al. , Mol Biol Cell, 2023, Jun 1;34(7):ar76 PMID: 37126397
  • Hazheen K, .et al. , J Biol Chem, 2020, August 20
  • Biological Activity
    Discription Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.
    Targets
    Target Value
    Product Information
    Catalog Num A13250
    Formula C21H27N7O
    Molecular Weight 393.5
    CAS Number 656820-32-5
    SMILES C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Warmed: 4 mg/mL (10.17 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.41 mL 127.06 mL 254.13 mL
    0.5 mM 5.08 mL 25.41 mL 50.83 mL
    1 mM 2.54 mL 12.71 mL 25.41 mL
    5 mM 0.51 mL 2.54 mL 5.08 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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