Sivelestat

Neutrophil elastase inhibitor

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Catalog No. A14184

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Sivelestat 10mg A14184-10
$65.00
Sivelestat 25mg A14184-25
$130.00
Sivelestat 50mg A14184-50
$240.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase).

Sivelestat

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Chemical Information

Catalog Num A14184
Actions Inhibitor
M. Wt 434.46
Formula C20H22N2O7S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 127373-66-4
Synonyms Elastase Inhibitor IV
SMILES code CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O
Chemical Name N-(2-(((4-(2,2-Dimethyl-1-oxopropoxy)phenyl)sulfonyl)amino)benzoyl)glycine

Biological Activity

Description
Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase).
Targets
neutrophil elastase

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