Sivelestat sodium hydrate (ONO-5046 sodium hydrate)

Catalog No.: A16137
Neutrophil elastase inhibitor
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
Grouped product items
Product Name Price Stock Qty
Sivelestat sodium 10mg
$80.00
In stock
Sivelestat sodium 50mg
$260.00
In stock
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Biological Activity
Discription Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
Targets
Target Value
Product Information
Catalog Num A16137
Formula C20H21N2O7S.4H2O.Na
Molecular Weight 528.51
CAS Number 201677-61-4
SMILES O=S(C1=CC=C(OC(C(C)(C)C)=O)C=C1)(NC2=C(C(NCC([O-])=O)=O)C=CC=C2)=O.[Na+].O.O.O.O
Synonyms ONO5046-Na, EI546 sodium, LY544349 sodium
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 91 mg/mL (172.18 mM)
Water Insoluble
Ethanol 91 mg/mL (172.18 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.92 mL 94.61 mL 189.21 mL
0.5 mM 3.78 mL 18.92 mL 37.84 mL
1 mM 1.89 mL 9.46 mL 18.92 mL
5 mM 0.38 mL 1.89 mL 3.78 mL
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