Biological Activity
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
Targets
neutrophil elastase | ||||
In vitro | DMSO | 91 mg/mL (172.18 mM) | |
Water | Insoluble | ||
Ethanol | 91 mg/mL (172.18 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.92 mL | 94.61 mL | 189.21 mL |
0.5 mM | 3.78 mL | 18.92 mL | 37.84 mL |
1 mM | 1.89 mL | 9.46 mL | 18.92 mL |
5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
*The above data is based on the productmolecular weight 528.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16137 |
---|---|
Actions | Inhibitor |
CAS No. | 201677-61-4 |
Formula | C20H21N2O7S.4H2O.Na |
M. Wt | 528.51 |
Purity | >98% |
Synonyms | ONO5046-Na, EI546 sodium, LY544349 sodium |
SMILES | O=S(C1=CC=C(OC(C(C)(C)C)=O)C=C1)(NC2=C(C(NCC([O-])=O)=O)C=CC=C2)=O.[Na+].O.O.O.O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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