Sivelestat sodium hydrate (ONO-5046 sodium hydrate)

Catalog No.: A16137

Neutrophil elastase inhibitor

Sivelestat sodium hydrate (ONO-5046 sodium hydrate)

Sivelestat sodium hydrate (ONO-5046 sodium hydrate) Chemical Structure

CAS NO. 201677-61-4

Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.

Availability: In stock

Package Price Qty
10 mg
$80.00
50 mg
$260.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
Targets
neutrophil elastase
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.92 mL 94.61 mL 189.21 mL
0.5 mM 3.78 mL 18.92 mL 37.84 mL
1 mM 1.89 mL 9.46 mL 18.92 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 528.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16137
Actions Inhibitor
M. Wt 528.51
Formula C20H21N2O7S.4H2O.Na
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 201677-61-4
Synonyms ONO5046-Na, EI546 sodium, LY544349 sodium
SMILES O=S(C1=CC=C(OC(C(C)(C)C)=O)C=C1)(NC2=C(C(NCC([O-])=O)=O)C=CC=C2)=O.[Na+].O.O.O.O

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